Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMTGTLGTLVPIILMFAVLYFLLIRPQQKQQKAVRQMQEELKKGDSVVTIGG----LHGTVDSIDES--KVVIK-TG-DN-TRLTFDRRAIREVSAAE 3P8B Chain:B ((89-145)) -------------------------------------VSGLEPGDLVEVIAGPFKGQKAKVVKIDESKDEVVVQFIDAIVPIPVTIKGDYVRLI----

General information: TITO was launched using: RESULT: Template: 3P8B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 145 3091 21.31 64.39 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain B : 0.57 3D Compatibility (PKB) : 21.31 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.685

(partial model without unconserved sides chains): PDB file : Tito_3P8B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P8B-query.scw PDB file : Tito_Scwrl_3P8B.pdb: