Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIDPNSIGAVTEPMLFEWTDRDTLLYAIGVGAGTGDLAFTTENSHGIDQQVLPTYAVICCPAFGA---AAKVGTFNPAALLHGSQGIRL---HAPLPAAGKLSVVTEVADIQDKGEGKNAIVVLRGRGCDPESGSLVAETLTTLVLRGQGGFGG-A--RG--ER---------------P-------AA-----------------------------------PEFPD--------------------------R--------------HPDARIDMPTREDQALIYRLSGDRNPLHSDPWFATQLAGFPKPILHGLCTYGVAGRALVAELGGGVAANITSIAARFTKPVFPGETLSTVIWRTEP--GRAVFRTEVAGSDGAEARVVLDDGAVEYVAG 2UV8 Chain:G ((1268-1642)) -----------IKGKDFEITAKEVYDFTHAVGNN--CEDFVSRPDR--TMLAPMDFAIVVGWRAIIKAIFPNTVDGDLLKLVHLSNGYKMIPGAKPLQVGDVVSTTAVIESVVNQPT--GKIVDVVGTLSR--NGKPVMEVTSSFFYRGNYTDFENTFQKTVEPVYQMHIKTSKDIAVLRSKEWFQLDDEDFDLLNKTLTFETETEVTFKNANIFSSVKCFGPIKVELPTKETVEIGIVDYEAGASHGNPVVDFLKRNGSTLEQKVNLENPIPIAVLDSYTPSTNEPYARVSGDLNPIHVSRHFASY-ANLPGTITHGMFSSASVRALIENWAADSVSSRVRGYTCQFVDMVLPNTALKTSIQHVGMINGRKLIKFETRNED---DVVVLT-GEAEIEQ-

General information: TITO was launched using: RESULT: Template: 2UV8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -131799 for 2067 contacts (-63.8/contact) + 2D Compatibility (PS) -27942 + (NN) -5483 + (LL) 372 1D Compatibility (HY) -7200 + (ID) 2950 Total energy: -175002.0 ( -84.66 by residue) QMean score : 0.400

(partial model without unconserved sides chains): PDB file : Tito_2UV8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2UV8-query.scw PDB file : Tito_Scwrl_2UV8.pdb: