Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAPPVHDRAHHPVRDVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNGITGPELMDEMREQALRFGADLRMEDVESVSLHGPLKSVVTADGQTHRARAVILAMGAAARYLQVPGEQELLGRGVSSCATCDGFFFRDQDIAVIGGGDSAMEEATFLTRFARSVTLVHRRDEFRASKIMLDRARNNDKIRFLTNHTVVAVDGDTTVTGLRVRDTNTGAETTLPVTGVFVAIGHEPRSGLVR-EAIDVDPDGYVLVQGRTTSTSLPGVFAAGDLVDRT--YRQAVTAAGSGCAAAIDAERWLAEHAATGEADSTDALIGAQR 3F8R Chain:D ((17-318)) ---------------DVIIVGLGPAAYGAALYSARYMLKTLVI-GETPGGQLTEAGIVDDYLGLIE-IQASDMIKVFNKHIEKYEVPVLLDIVEKIENRGDEFVVKTKRKGEFKADSVILGIGVKRRKLGVPGEQEFAGRGISYCSVCDAPLFKNRVVAVIGGGDSALEGAEILSSYSTKVYLIHRRDTFKAQPIYVETVKKKPNVEFVLNSVVKEIKGDKVVKQVVVENLK--------VNGVFIEIGFDPPTDFAKSNGIETDTNGYIKVD-EWMRTSVPGVFAAGDCTSAWLGFRQVITAVAQGAVAATSAYRYVTE------------------

General information: TITO was launched using: RESULT: Template: 3F8R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -214011 for 2551 contacts (-83.9/contact) + 2D Compatibility (PS) -30655 + (NN) -3778 + (LL) 1844 1D Compatibility (HY) -24400 + (ID) 5550 Total energy: -276550.0 ( -108.41 by residue) QMean score : 0.537

(partial model without unconserved sides chains): PDB file : Tito_3F8R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3F8R-query.scw PDB file : Tito_Scwrl_3F8R.pdb: