TITO

Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)

Input alignment information:

Query sequence

---------MEELLERVFSFS-DVDKLIDFISYELQKPVILESADFFLLAYNSYYINHFDSANQQTIFSKKCPVQIFERFLKDGIIEKLKTEPEPFRVNKIESIGLN---QRVVVSAKHKGEVMGYIWIQELDQNLTDEELDFLYETSFHVGKIIYKTNKLKQEKEEKAEDLIKRAIYQQFTSEKELRREAERINTVLPSMFSVVILHAANGDGEAVEDLKENIRSYLNLRDKVSHVLTIESNIVIVVASFSQKSSVSSAASEFINKLLTHFHFQKIPTPIYIGIGNEYNHLLKLGKSYTEALEVIKAAEITGNQENIPYEYAKLGIYRYLESIEQKNEFLEYENKDLALLKAKDEESSTELLKTLEIYLLNNCKTKPAAEQLFIHQNTLNYRIKQITEMTSIDLSDFRTRCQLYLDLMLMKKK

2B18 Chain:A ((10-164))

MALLQKTRIINSMLQAAAGKPVNFKEMAETLRDVIDSNIFVVSRRGKLLGYSINQ-QIENDRMKKMLEDRQFPEEYTKNLFNVPETSSNLDINSEYTAFPVENRDLFQAGLTTIVPIIGGGERLGTLILSRLQDQFNDDDLILAEYGATVVGMEIL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information:

TITO was launched using:	RESULT:
Template: 2B18.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output	Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 646 -75885 -117.47 -534.40 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -117.47 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.442

(partial model without unconserved sides chains):
PDB file : Tito_2B18.pdb:

(Unconserved sides chains are recalculated) :
Sequence: align-2B18-query.scw
PDB file : Tito_Scwrl_2B18.pdb: