Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPR---ELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALL-QGFNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKG-VSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST 4CQG Chain:A ((11-263)) ---------YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSD-----LPRVKTEIDALKSLRHQHICQLYHVLETKN-KIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHSQGYAHRDLKPENLLFDENHKLKLIDFGLC-AK-----------CGSLAYAAPELIQG-----SEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSIL--LLQQMLQVDPKKRISMRNLLNHPWVMQD

General information: TITO was launched using: RESULT: Template: 4CQG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -143834 for 1783 contacts (-80.7/contact) + 2D Compatibility (PS) -24705 + (NN) -12297 + (LL) 1664 1D Compatibility (HY) -26400 + (ID) 4950 Total energy: -210522.0 ( -118.07 by residue) QMean score : 0.397

(partial model without unconserved sides chains): PDB file : Tito_4CQG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CQG-query.scw PDB file : Tito_Scwrl_4CQG.pdb: