Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEE-----VIEEIP-EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQR-------YRSQDLAKAILPSLDNLERALAVEG----LTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDEHPADSIAEVFQKGYKLHERLLRPAMVVVYN 3J6V Chain:K ((25-197)) ---AGVPAPTIHMSAQQMQDAAAKEEVEKAETPAPAPSRSSFSIYPPIPGQESSLRWAGKKFEEIPIAHIKASYNNTQIHVVSAA-HQPLARASCGTEGFRNAKKGTGIAAQTAGIAAAAKATGKGVTHVRVVVKGLGPGRLSAIKGLTMGGLEVISITDNT--------PIPHNGCRP--------RKARRL--------------

General information: TITO was launched using: RESULT: Template: 3J6V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 101681 for 1163 contacts (87.4/contact) + 2D Compatibility (PS) -15393 + (NN) 3674 + (LL) 3768 1D Compatibility (HY) -2000 + (ID) 1850 Total energy: 89880.0 ( 77.28 by residue) QMean score : 0.118

(partial model without unconserved sides chains): PDB file : Tito_3J6V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3J6V-query.scw PDB file : Tito_Scwrl_3J6V.pdb: