Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVFLIGANGQIGQRLVSLFQDNPDHSIRAMVRKEEQKASLEAAGAEAVLANLEGSPEEIAAAAKGCDAIIFTAGSGGSTGYDKTLLVDLDGAAKAIEAAAIAGIKRFIMVSALQAHNRENWNEALKPYYVAKHYADKILEASGLTYTIIRPGGLRNEPGTG--TV------SAA-KDLERGFISRDDVAKTVIASLDEKNTENRAFDLTEGDTPIAEALKKL 3E48 Chain:A ((1-210)) MNIMLTGATGHLGTHITNQAIANHIDHFHIGVRNVEKVPDDWRGKVSVRQLDYF-NQESMVEAFKGMDTVVFIPSIIHPS------FKRIPEVENLVYAAKQSGVAHIIFIGYYADQHNNPF--HMSPY---FGYASRLLSTSGIDYTYVRMAMYMDPLKPYLPELMNMHKLIYPAGDGRINYITRNDIARGVIAIIKNPDTWGKRYLLSGYSYDMKELAAI-

General information: TITO was launched using: RESULT: Template: 3E48.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 971 -138512 -142.65 -689.11 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -142.65 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.478

(partial model without unconserved sides chains): PDB file : Tito_3E48.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3E48-query.scw PDB file : Tito_Scwrl_3E48.pdb: