Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIVRIETFPLFHRLEKPYGDANGFKRYRTCYLIRIITESGIDGWGECVDWLP---ALHVGFTKRIIPFLLGKQAGSRLSLVRT----------IQKWHQRAASAVSMALTEIAAKAADCSVCELWGGRYREEIPVYASFQSYSDSPQWISRSVSNVEAQLKKGFEQIKVKIGGT-SFKEDVRHINALQHTAGSSITMILDANQSYDAAAAFKWERYFSEWTNIGWLEEPLPFDQ-PQDYAMLRSRLSVPVAGGENMKGPAQYVPLLSQRCLDIIQPDVMHVNGIDEFRDCLQLARYFGVRASAHAYDGSLSRLYALFAQACLPPWSKMKNDHIEPIEWDVMENPFTDLVSLQPSKGMVHIPKGKGIGTEINMEIVNRYKWDGSAY 4H83 Chain:A ((20-385)) LTITRIETIPMVAPL----------MTHRATIVTRVHTDAGIIGEAYTGDEHETMFDIDRIIHEELAPTLIGQDAMAIERLWDSGYKVTFDILRDRRLGLVALAAVNTAIWDAVGKALKMPLWKLWGGYRN-ELPMIAIGGYYGEPL-GSI--ADEMHNYQELGLAGVKFKVGGLSA-AEDAARITAAREAAGDDFIICIDANQGYKPAVAVDLSRRIAD-LNIRWFEEPVEWHNDKRSMRDVRYQGSVPVCAGQTEFSASGCRDLMETGAIDVCNFDSSWSGGPTAWLRTAAIATSYDVQMGHHEEP-----QVSTHLLASQPH-GTIAECFHPDRDP-FW-WNMI-TNRPKLNNGTLTLSDRPGLGWDLNWDYIDQYRV-----

General information: TITO was launched using: RESULT: Template: 4H83.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2102 -212180 -100.94 -622.23 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -100.94 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.387

(partial model without unconserved sides chains): PDB file : Tito_4H83.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4H83-query.scw PDB file : Tito_Scwrl_4H83.pdb: