Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKAVSVILTLSLFLLTACSLEPPQWAKPSNSGNKKEFTIGLSVSTLNNPFFVSLKKGIEKEAKKRGMKVIIVDAQNDSSKQTSDVEDLIQQGVDALLINPTDSSAISTAVESANAVGVPVVTIDRSAEQ-GKVETLVASDNVKGGEMAAAFIADKLGKGAKVAELEGVPGASATRERGSGFHNIA-DQKLQVVTKQS-ADFDRTKGLTVMENLLQGHPDIQAVFAHNDEMALGALEAINSSGK---DILVIGFDGNKDALASIKDRKLSATVAQQPELIGKLATEAADDILHGKK-VQKTISAPLKLETQK 4KQ9 Chain:A ((6-282)) -----------------------------------AGKKVVYSTFGAQIPFFNRIGEGAKAQATVRRLDFDISTSEIDPGKQIDSIDNAVAQQPDGLIVSPIDGSALVPTIKGAVEDGVPVILLADGLSEDVGQLSFVGSDFAEIGRLKATYIADRLGDGGTVAMVNGTRGMSFVEEQGEAAREVFEERGIEIVDDVYTKAITPDEGLTATQNILTRHSDVGAIYYSGDDGALGGIRAIAARNIAPGKIMVVGTDANEGALAAVRAGTMALTVSQCAYEQGGIAIDVMADYLETGKKPDRRIFTPVIEIDTE

General information: TITO was launched using: RESULT: Template: 4KQ9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1501 3818 2.54 14.14 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : 2.54 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.609

(partial model without unconserved sides chains): PDB file : Tito_4KQ9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4KQ9-query.scw PDB file : Tito_Scwrl_4KQ9.pdb: