Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --MGFTDETVRFRLDDSNKVEISETLTAVYR-SLEEKGYNPINQIVGYVLSGDPAYV--PRYNDARNQIRKYERDEIVEELVRYYLQGNGIDL------ 2CBL Chain:A ((218-305)) THPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLG----QWAIGYVTADGNILQTIPHNKPLFQALIDGFREG-------FYLFPDGRNQNPDLTG

General information: TITO was launched using: RESULT: Template: 2CBL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -4157 for 488 contacts (-8.5/contact) + 2D Compatibility (PS) -8448 + (NN) -2569 + (LL) 1148 1D Compatibility (HY) -800 + (ID) 650 Total energy: -15476.0 ( -31.71 by residue) QMean score : 0.184

(partial model without unconserved sides chains): PDB file : Tito_2CBL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CBL-query.scw PDB file : Tito_Scwrl_2CBL.pdb: