Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSRSVCEK--MTMTTENPNQTVVSHFFLEGLR--------YTAKHSSLFFLLFLLIYSI----TVAGNLLILLTVG--SDSHLSLPMYHFLGHLSFLDACLSTVTV-------PKVMAGLL--TLDGKVISFEGCAVQLYCFHFLASTECF-------------------------LYTVMAYDRYLAICQPLHYPVAMNRRMCAEMAG---ITWAIGATHAAIHTSLTFRLLYCGPCHIAYFFC-------------------------------------------------------DIPPVLKLACTDTTINELVMLASIGIVAAGCLILIVISYIFIVAAVLRIRTAQGRQRAFSPCTAQLTGVLLYYVPPVCIYLQPRSSEAGAGA----PAVFYTIVTPMLNPFIYTLR----NKEVKHALQRLLCSSFRESTAGSPPP--------------------- 4AN8 Chain:A ((8-500)) LEKFNLIDEPWIPVLKGGRVVEVGIGEALLRAHEFARIETPSPLEEAVLHRLLLAVLHRALSGPRCPEDVLDWWRKGGFPQDPIRDYLNRFRDRFFLFHPEAPFLQVADLPEENPLPWSKLLPELANLPKATYAQAARALLVHQAFAPGGLLRRYGVGSAKDAPVARPALFLPTGQNLLETLLLNLVPYTPEDDAPIWEVPPLRLGDLEGARTKWPLTGRTRVYTWPARGVRLLDEGDGVRFMGYGPGVEPLEATHRDPMVAQRLDAKGNLLVLRLSEERSFWRDFSAMLPRQGGKVAATLEHAENLQGELEDEGLEGRITLRVLGQVSDQAKVLDIRREVYPLPSGLLTPKAEENLEKALKMAEELGQGLKHLAQEVAKAVVYLEELTKLANSLPLERLYWHALDGAFPRFFARVEEEASLDLWREALRGAALEAWKATRRFLGTGARHLKALAQGEQEFGRLLGEL

General information: TITO was launched using: RESULT: Template: 4AN8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -307960 for 2287 contacts (-134.7/contact) + 2D Compatibility (PS) -33552 + (NN) 5517 + (LL) 0 1D Compatibility (HY) -4800 + (ID) 1850 Total energy: -342645.0 ( -149.82 by residue) QMean score : 0.171

(partial model without unconserved sides chains): PDB file : Tito_4AN8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4AN8-query.scw PDB file : Tito_Scwrl_4AN8.pdb: