Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLVDSFNRVIDYIRVSVTKQCNFRCQYCMPTTPLDFFDDEELLPLDNVLEFLKIAIDEGVKKIRI--TGGEPLLRKGLDEFIAKLHAYNKEVALVLSTNGFSL-KKMAKGLKDAGLSRVNVSLDSLKSDRVLKISQKDALKNTLEGIEESLKVGLKLKLNTVVMKGVNDDEILELLEYAKNRSIQIRYIEFMENTHAKSLVKGLKEKEILDLIAQKYKIMGMEKPKQGSSKIYTLENGYQFGIIAPHSDDFCQSCNRIRLASDGKICPCLYYQDAIDAKEAIINKDTKMMKRLLKQSIINKPEKNMWNDKNGGTPTRAFYYTGG 4M7T Chain:A ((21-270)) -----MDKLFSMIEVEVNSQCNRTCWYCPNSVSKR--KETGEMDPALYKTLMEQLSSLDFAGRISFHFYGEPLLCKNLDLFVGMTTEYIPRARPIIYTNGDFLTEKRLQTLTELGIQKFIVTQHAGAKHKFRGVYDQ--------------------------------------LAGADKEKVVYLDHSDLVLSNRGGILDNIPANMSCMVPSNLAVV-------------------TVLGNVLPCFEDF-NQKMVMGNIGEQHISDIWHNDKFTSFRKMLKEGHRGKSDLCKNCNNVSVQTEEQYDYVL-------------

General information: TITO was launched using: RESULT: Template: 4M7T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -60770 for 1998 contacts (-30.4/contact) + 2D Compatibility (PS) -25396 + (NN) -7044 + (LL) 4216 1D Compatibility (HY) -5200 + (ID) 1700 Total energy: -95894.0 ( -47.99 by residue) QMean score : 0.334

(partial model without unconserved sides chains): PDB file : Tito_4M7T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4M7T-query.scw PDB file : Tito_Scwrl_4M7T.pdb: