Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKQLIQSEEEFKRIAE--QEGVFVFLKHSTTCPISQAAFHEFDAFANQHEDVPAYYLQVQEARPLSNFIAETYGVKHESPQIFIIQNGEVKWHTSHSQITEAAIEQHLS 4AJ8 Chain:A ((2-101)) --VYQVKDQEDFTKQLNEAGNKLVVIDFYATWCGPCKMIAPKLEELSQSMSDVVFLKVDVDECED----IAQDNQIAC--PTFLFMKNGQKLDSLS-G-ANYDKLLELV-

General information: TITO was launched using: RESULT: Template: 4AJ8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 403 -7454 -18.50 -76.84 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -18.50 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.683

(partial model without unconserved sides chains): PDB file : Tito_4AJ8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4AJ8-query.scw PDB file : Tito_Scwrl_4AJ8.pdb: