Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKHTFVLFLSLILLVLPGCSAEKSSADTAKKTLTIYSTMSTDSERDTFRKLAAAFEKEHSDIHVSLHF-PGNDYENMMRVRMAANDLPDLFDTHG--WGKIRYGEYTADLRDMKW-----TQDLDPNLNSILKNKSGKVYAYPINQAKDGLAYNRNILDRYGIAP---PETMDDFIKALRTIKEKSKGSIVPFWFAGYDKSSFAQYYDQFATPLLITDPAHNEKKQLINGT--FQW-S-KFTYLSEILKQMQKEKLINIDAVTAKKSQ-LIELMAQNKIAFTMQGGTLGQDVAQINPNVKVGIIPTPAIHPGDDPIWIGGERYTLAAWKDSPQLKEAKDFIAFMARPANAKQMAEATSLPSGLTNVKAD--IFYANDY-EYYQDVKVE--PYF-DR---L-YLPNGMWD-VLGTVGQELAADILAPQDISQKLGREYKRLREQSETQGAENNE 4R6K Chain:A ((32-427)) ----------------------------EDVTLRIAWWGG-QPRHDYTTKVIELYEKKNPHVHIEAEFANWDDYWKKLAPMSAAGQLPDVIQMDTAYLAQYGKKNQLEDLTPYTKDGTIDVSSIDENMLSG-GKIDNKLYGFTLGVNVLSVIANEDLLKKAGVSINQENWTWEDYEKLAYDLQ-E-KAGVYGSNGM----HPPDI-FFPYYLRT----KGERFYKE--DGTGLAYQDDQLFVDYFERQLRLVKAKTSPTPDESAQIKGMEDDFIVKGKSAITWNYSNQYLGFARL-TDSPLSLYLPPEQMQEKA-LTL-KPSMLFSIPKSSEHKKEAAKFINFFVNNEEANQLIKGERGVPVSDKVADAIKPKLNEEETNIVEYVETASKNISKADPPEPVGSA--EVIKLLKDTSDQILYQKVSPEKAAKTFRKKANEILERN---------

General information: TITO was launched using: RESULT: Template: 4R6K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1932 49429 25.58 133.95 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 25.58 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.418

(partial model without unconserved sides chains): PDB file : Tito_4R6K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4R6K-query.scw PDB file : Tito_Scwrl_4R6K.pdb: