Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAVCLVRHGETDWNLQQKCQGKTDIPLNATGERQARETGEYVKD--FSWDIIVTSPLKRAKRTAEIINEYLH---LPIVEMDDFKERDYGDAEGMPLEERTKRYPD-----N-----------------------------IYPNMETLEELTDRLMGGLAKVNQA--YPNKKVLIVAHGAAIHALLTEISGGDPE-LQSTRLVNACLSNIEFAE-EKWRIKDYNINSHLSGFIK 1RII Chain:A ((4-224)) TGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSGELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYADIGGGPLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVKHLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPL---------------

General information: TITO was launched using: RESULT: Template: 1RII.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 913 -70732 -77.47 -397.37 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -77.47 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.430

(partial model without unconserved sides chains): PDB file : Tito_1RII.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1RII-query.scw PDB file : Tito_Scwrl_1RII.pdb: