Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSVNLSYPIGEYKPRESISKEQKDKWIQVLEEVPAKLKQAVEVMTDSQLDTPYRDGGWTVRQVVHHLADSHMNSYIRFKLSLTEETPAIRP--YD--EK-AWS--ELKDSKTADPSGSLALLQELHGRWTALLRTLTDQQFKRGFYHPDTK--EIITLENALGL-YVWHSHHHIAHITELSRRMGWS 5CIV Chain:A ((16-183)) -------------------EYTSKEELKKTIHAAYLLLDGEFEGIDDSQKDNRVPEVDRTPAEIIAYQLGWLHLVMGWDRDELAGKPVIMPAPGYKWNQLGGLYQSFYAAYADLSLTELRRLFRDTERQWLDWIDTLSEEDLFTQSVRKWTGDKPNWPMARWIHINSAAPFKTFRAKIRKWKKHQRQ-

General information: TITO was launched using: RESULT: Template: 5CIV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 604 -33943 -56.20 -214.83 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -56.20 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.478

(partial model without unconserved sides chains): PDB file : Tito_5CIV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CIV-query.scw PDB file : Tito_Scwrl_5CIV.pdb: