Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNYYTTAETPLGELIIAEEEDRITRLFLSQEDWVDWKETV---QNTEH-KETPNLAEAKQQLQEYFAGERK--TFSLPL-SQ---KGTPFQQK-VWQALERIPYGESRSYADIAAAVGSPKAVRAVGQANKRNDLPIFVPCHRVIGKNSALTGYAGSKTEIKAFLLNIERISYKEK 1EH6 Chain:A ((7-179)) -MKRTTLDSPLGKLELSGCEQGLHEIKLLG----------EVPAPAAVLGGPEPLMQCTAWLNAYFHQPEAIEEFPVPALHHPVFQQESFTRQVLWKLLKVVKFGEVISYQQLAALAGNPKAARAVGGAMRGNPVPILIPCHRVVCSSGAVGNYS-GGLAVKEWLLAHEGHRLGKP

General information: TITO was launched using: RESULT: Template: 1EH6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 708 -64046 -90.46 -418.60 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -90.46 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.512

(partial model without unconserved sides chains): PDB file : Tito_1EH6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EH6-query.scw PDB file : Tito_Scwrl_1EH6.pdb: