Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTGYFLLEDGNKIEFELYPEAAPGTVANFEKLAN--EGF-YDGLTFHRVIPGFVSQGG-CPHGTGTGGPG-YTIKCETEGNPHTHEA-GALSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGKVTSGLEFAKNM-----SNGDVMKEVRVEG 3ODI Chain:S ((19-158)) ------------RVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITI--

General information: TITO was launched using: RESULT: Template: 3ODI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain S - contact count / total energy / energy per contact / energy per residue : 636 30125 47.37 233.53 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain S : 0.77 3D Compatibility (PKB) : 47.37 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.522

(partial model without unconserved sides chains): PDB file : Tito_3ODI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ODI-query.scw PDB file : Tito_Scwrl_3ODI.pdb: