Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTICVFAGSNPGGNEAYKRKAAELGVYMAEQGIGLVYGGSRV-GLMGTIADAIMENGGTAIGVMPSGLFSGEVVHQNLTELIEVNGMHERKAKMSELADGFISMPGGFGTYEELFEVLCWAQIGIHQKPIGLYNVNGYFEPMMKMVKYSIQEGFSNESHLKLIHSSSRPDELIEQMQNYSYPILEKKWTEI 3SBX Chain:A ((14-188)) -WTVAVYCAAAP-THPELLELAGAVGAAIAARGWTLVWGGG-HVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDALQACA--------------

General information: TITO was launched using: RESULT: Template: 3SBX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 908 -66327 -73.05 -381.19 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -73.05 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.466

(partial model without unconserved sides chains): PDB file : Tito_3SBX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3SBX-query.scw PDB file : Tito_Scwrl_3SBX.pdb: