Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEELLERVFSFSDV--------DKLIDFISYELQKPVILESADFFLLAYNSYYINHFDSANQQTIFSKKCPVQIFERFLKD--GIIEKLKTEPEPFRVNK-------------------------------------IESIG----LNQRVVVSAKHKGEVMGYIWIQELDQNLT---DEELDFLYETSF--HVGKIIYKTNKLKQEKEEKAEDLIKRAIYQQFTSEKEL------RREAERINTVLP----------SMFSVVILHAANGDGEAVEDLKENIRSYLNLRDKVSHVLTIESNIVIVVASFSQKSSVSSAASEFINKLLTHFHFQKIP-------------------------TPIYIGIGNEYNHLLKLGKSYTEALEVIKAAEITGNQENIPY----------EYAKLG-----------IYRYLESIEQ--KNEFLEYEN--KDLALL----KAKDEESSTELLKTLEIYLLN------NCKTKPAAEQLFIHQNTLNYRIKQITEMTSI--DLSDFRTRCQLYLDLMLMKKK------ 4U1C Chain:C ((251-794)) QEDFFTRLQTIIDSRGKKTVNQQSLISTLEELLTVA---EKPYEFIMAYLTLIPSRFDASANLS----YQPIDQWKSSFNDISKLLSILDQTIDTYQVNEFADPIDFIEDEPKEDSDGVKRILGSIFSFVERLDDEFMKSLLNIDPHSSDYLIRLRDEQSIYNLILRTQLYFEATLKDEHDLERALTRPFVKRLDHIYYKSENLIKIMETAAWNIIPAQFKSKFTSKDQLDSADYVDNLIDGLSTILSKQNNIAVQKRAILYNIYYTALNKDFQTAKDMLLTSQVQTNINQFDSSLQILFNRVVVQLGLSAFKLCLIEECHQILNDLLSSSHLREILGQQSLHRISLNSSNNASADERARQCLPYHQHINLDLIDVVFLTCSLLIEIPRMTAFYSGIKVKRIPYSPKSIRRSLEHYDKLSFQGPPETLRDYVLFAAKSMQKGNWRDSVKYLREIKSWALLPNMETVLNSLTERVQVESLKTYFFSFKRFYSSFSVAKLAELFDLPENKVVEVLQSVIAELEIPAKLNDEKTIFVVEKGDEITKLEEAMVKL

General information: TITO was launched using: RESULT: Template: 4U1C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1409 -147000 -104.33 -363.86 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain C : 0.67 3D Compatibility (PKB) : -104.33 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.330

(partial model without unconserved sides chains): PDB file : Tito_4U1C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4U1C-query.scw PDB file : Tito_Scwrl_4U1C.pdb: