Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MEDYTKIEKIGEGTYGVVYKGRHK--TTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLM--QDSRLYLIFEFLSMDLKKYLDSI----PPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLI----DDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSE----IDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKP-----GSLASH----VKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM |
| 4F6U Chain:A ((27-340)) | -------CKVGRGTYGHVYKAKRKDGKDDKDYALKQIE----GTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASK---VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGF--------------VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQENPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLED------- |
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General information:
TITO was launched using:
| RESULT:
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Template: 4F6U.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
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3D Compatibility (PKB) -132739 for 1958 contacts (-67.8/contact) +
2D Compatibility (PS) -27378 + (NN) -9372 + (LL) 2256
1D Compatibility (HY) -28400 + (ID) 5600
Total energy: -201233.0 ( -102.77 by residue)
QMean score : 0.400
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