Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MEDYIKIEKIGEGTYGVVYKGRHR--VTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLM--QDSRLYLIFEFLSMDLKKYLDSI----PPGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLI----DDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSE----IDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPG-----SLASH----VKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDNQIKKM |
| 4F6U Chain:A ((27-340)) | -------CKVGRGTYGHVYKAKRKDGKDDKDYALKQIE----GTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASK---VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGF--------------VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQENPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLED------- |
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General information:
TITO was launched using:
| RESULT:
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Template: 4F6U.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
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3D Compatibility (PKB) -131926 for 1950 contacts (-67.7/contact) +
2D Compatibility (PS) -27278 + (NN) -10247 + (LL) 2408
1D Compatibility (HY) -27600 + (ID) 5500
Total energy: -200143.0 ( -102.64 by residue)
QMean score : 0.378
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