Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFIHIVGPGDSLFSIGRRYGASVDQIRGVNGLDETNIVPGQALLIPLYVYTVQPRDTLTAIAAKAFVPLERLRAANPGISPNALQAGAKITIPSISNYIAGTLSFYVLRNPDL-DRELINDYAPYSSSISIFEYHIAPNG------------------------DIA-NQL-ND-------------------AAAIETT--WQRRVTPLATITNLTSGGFSTEIVHQVLNNPTARTNLVNNIYDLVSTRGY-GGVTIDFEQVSA-----------ADRDLFTGFLRQLRDRLQAG------GYVLTIAVPAKTSDNIPWLRGYDYGGIGAVVNYMFIMAYDWHHAG-SEPGPVAPIT---------------------------EIRRTIEFTIA-QVPSRKIIIGVPLYGYDWIIPYQP-----GT-------------------VASAISNQNAIERAMR------YQAPIQYSAEYQSPFFRYSDQQGRTHEVWFEDVRSMSRKMQIVREYRLQAIGAWQLTLGFTPGPWLLRKFFTIRKV 3ARX Chain:A ((136-563)) -------------------------------------------------------------------------------------------------PSIVMGTYFVEWGIYGRDYTVDNMPVDNLTHILYGFIPICGPNESVKSVGGNSFNALQTACRGVNDYEVVIHDPWAAYQKSFPQAGHEYSTPIKGNYAMLMALKQRNPDLKIIPSIGGWTL----SDPFYDF-VDKKNRDTFVASVKKFLKTWKFYDGVDIDWEFPGGGGAAADKGDPVNDGPAYIALMRELRVMLDELEAETGRTYELTSAIGVGYD----KIEDVDYADAVQYMDYIFAMTYDFYGGWNNVPGHQTALYCGSFMRPGQCDGGGVDENGEPYKGPAYTADNGIQLLLAQGVPANKLVLGTAMYGRGWEGVTPDTLTDPNDPMTGTATGKLKGSTAQGVWEDGVIDYKGIKSFMLGANNTGINGFEYGYDAQAEAPWVWNRS---TGELITFDDHRSVLAKGNYAKSLGLAGLFSWEIDADNGDILNAMH--------

General information: TITO was launched using: RESULT: Template: 3ARX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1726 -206519 -119.65 -681.58 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -119.65 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.400

(partial model without unconserved sides chains): PDB file : Tito_3ARX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ARX-query.scw PDB file : Tito_Scwrl_3ARX.pdb: