Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELYIITGASKGLGQAIALQALEKGHEVHALSRTKTDVSHKKLTQHQIDLINLEEAEQQFETLLSSIDSDRYSGITLINNAGMVTPIKRAGEASLDELQRHYQLNLTAPVLLSQLFTKRFASYSGKKTVVNITSGAAKN----------------------------PYKGWSAYCSSKAGLDMFTRTFGFEQEDEELPVNMISFSPGVMDTEMQAVIRSSSKKDFHHIERFRKLNETGSLRSPDFIAGTLLSLLEKG--TENGRIYDIKEFL 1FJH Chain:A ((1-245)) MSIIVISGCATGIGAATRKVLEAAGHQIVGIDIRDA--------EVIADLSTAEGRKQAIADVLAKC---SKGMDGLVLCAGLGPQ--------TKVLGNVVSVNYFGATELMDAFLPALKKG-HQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNALTVAVRKRAAAWG--EAGVRLNTIAPGA------------------------FVPPMGRRAEPSEMASVIAFLMSPAASYVHGAQIVID---

General information: TITO was launched using: RESULT: Template: 1FJH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1023 -77306 -75.57 -398.48 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -75.57 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.522

(partial model without unconserved sides chains): PDB file : Tito_1FJH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1FJH-query.scw PDB file : Tito_Scwrl_1FJH.pdb: