Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MERKTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHAALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHE----DHDKPEEEVVEEIVKVAGMFAVDAITTNNELFI--APMAKACERLGLR--GAGVQAAENARDKNKMRAAFNRAGVKSIKNKRV--TTLEDFRAALQEIGTPLILKPTYLASSIGVTLIKEMETAEAEFNRVNEYLKSINVPKAVTFEAPFIAEEFLQGE-YDDWYETSGYSDYISIEGIMA-DGEYFPVAIHDKTPQIGFTETSHITPS-ILDDDAKRKIVEAAKKANEGLGLENCATHTEIKLMKNREAGLIESAARFAGWNMIPNIKKVFGVDMAQLLLDVLCFGKEADLPKGLLEQEPCYVADCHLYPQHFKENGQLPETAVDFVIESIDIP----DGVLKGDTEIVSFSAAEAGTSVDLRLFEAFNSIAAFELKGSNSGDVAESIKQIQQQAKLTAKYALPV 3U9T Chain:A ((48-483)) -SIQRLLVANR--GEIACRVMRSARAL-GIG-----SVAVHSDIDRHARHV-----------------AEADIAVDLGGAKPADSYLRGDRIIAAA----LASGAQAIHPGYGFLSENADFARACEEAGLLFLGPPAAAIDAMGSKSAAKALMEEAGVPLVPGYHGEAQDLETFRREAGRIGYPVLLKAAA------MKVVEREAELAEALSSAQR--------------ARMLVEKYLLKPRH------------VEIQVFADRHGHCLYLNERDCSIQRRHQKVVEEAPAPGLGAELRRAMGEAAVRAAQAIGY-VGAGTVEFLLDERGQFFFMEMNTRLQVEHP--VTEAITGLDLVAWQIRVARGEALPLTQEQV-----------PLNGHAIEVRLYAEDPEGDFLPA--SGRLMLYREAAAGPGR-RVDSGVREGDEVSPF-YDPMLAKLIAW--GETREEARQRLLAMLAETSVG-------

General information: TITO was launched using: RESULT: Template: 3U9T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2171 8891 4.10 23.21 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 4.10 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.431

(partial model without unconserved sides chains): PDB file : Tito_3U9T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3U9T-query.scw PDB file : Tito_Scwrl_3U9T.pdb: