Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKHTAITTFILLGLTEDPQLQVLLFMFLFITYMLSVTGKLTIIALTMLDPHLKTPMYFFLQNLSFLEI-----SFTATCVPRFLYSISTGNKIITYNACVIQLFFADLFGVTEFFLLATMSYDRYVAICKPLHYMAIMSNKVCKTMVICCWMAALMIILPPLSLGFHLEFCDSNVINHFGCDALPILKIPCSDTSLIEQMVVASAVLTFIITLVCVVLSYTYIIRTILKFPSVQQKKKAFSTCSSHIT-----------VVSITYGSCIFIYIKPSAKEEVNINKGVSVLISSISPMLNSFIYTLRNEQVKQAFHDSLKKIAFRLKK 1F88 Chain:A ((33-315)) -----------------EPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTT-----LYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAF-TWVMALACAAPPL-VGWS-RYIPEGMQCSCGID----YYTPHEETN-NESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAA----SATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPSTT

General information: TITO was launched using: RESULT: Template: 1F88.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -184139 for 2055 contacts (-89.6/contact) + 2D Compatibility (PS) -26695 + (NN) -6864 + (LL) 3368 1D Compatibility (HY) -25200 + (ID) 3100 Total energy: -242630.0 ( -118.07 by residue) QMean score : 0.176

(partial model without unconserved sides chains): PDB file : Tito_1F88.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1F88-query.scw PDB file : Tito_Scwrl_1F88.pdb: