Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTQPSKTTKLTKDEVDRLISDYQTKQDEQAQETLVRVYTNLVDMLAKKYSKGKSFHEDLRQVGMIGLLGAIKRYDPVVGKSFEAFAIPTIIGEIKRFLRDKTWSVHVPRRI-KELGPRIKMAVDQLTTETQRSPKVEEIAEFLDVSEEEVLETMEMGKSYQALSVDHSIEADSDGSTVTILDIVGSQEDGYERVNQ-QLMLQSV---LHVLSDREKQII----DLTYIQNKSQKETGDILGISQMHVSRLQRKAVKKLREALIEDPSMELM 5IPM Chain:F ((101-317)) ----------------------------------------LVVKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHIVKELNVYLRTA-RELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNE--RITSVDTPLGGDSEKALLDIL--ADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLARRFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREIL---------

General information: TITO was launched using: RESULT: Template: 5IPM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 543 -47937 -88.28 -230.47 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain F : 0.71 3D Compatibility (PKB) : -88.28 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.446

(partial model without unconserved sides chains): PDB file : Tito_5IPM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5IPM-query.scw PDB file : Tito_Scwrl_5IPM.pdb: