Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVTYWTGENLTLRAIQPEDIVIFDSLDDEILRNMDSLHFPR---SANNMREWVEEQLEKD-EFRFIAVESDNNIVGMIETFDCDRKNGTFGYYLAVFEPYRGKGFAKEMILMVLRFFFLELAYQKVNTTVYSFNNPSIRLHEKLGFMKEGQLRKIIFTKGAYYDGICFGMTREEFELNHG 4JJX Chain:A ((5-157)) ----------LTLRALERGDLRFIHNLNNN--RNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQD----------------

General information: TITO was launched using: RESULT: Template: 4JJX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 542 -20593 -37.99 -138.21 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -37.99 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.597

(partial model without unconserved sides chains): PDB file : Tito_4JJX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JJX-query.scw PDB file : Tito_Scwrl_4JJX.pdb: