Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKEKLRLYHTNDLHSHFENW------------PKIVDYIEQKRKEHQSDGEETLVFDIGDHLDRFQFVTEATFGKANVDL--LNRLHIDGAAIGNNEGITLPHEELAALYDHAEFPVIVSNLFDKN-GNR--PSWAVPYHIKSLKNGMSIAFLGVTV--------PYYPVYDKLGWTVTDALESIKETILEVKGQADIIVLLSHLGILD----------DQAVAEAVP--EIDVILESHTHHLL----EDGQVV-------------NGVLLASAEKYGHYVGCVEITVDSVQ-RSINSK--TASVQNMAEW----------TGESAETK-------AFLNEKEREAEEKLSDAVAELAQDAEVKWFEESELPLLLAYALKEWCETDISMVNSGVILGPLKAGPVTKLDLHRICPHPINPVAVRLTGEELKETIVHAASEQMEQLRIKGLGFRGEVMGKMVYAGVEVETKRLDDGITHVTRITLNGEDIEKHKQYSVAVLDMFTLGKLFPLIRDAAEKEYFMPEFLRDLLAWKLAQ 1OI8 Chain:A ((8-477)) ---KITVLHTNDHHGHF--WRNEYGEYGLAAQKTLVDGI---RKEVAAEGGSVLLLSGGDI---NTGVCESDLQDAEPDFRGMNLVGYDAMAIGNHE-FDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWAL-FKRQDLK----IAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQE--LQQTEKPDIIIAATHMGHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCKPDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVLYTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAAQMDRTGADFAVMSGGGIRDSIEAGDISYKNVCKVQPFGNVVVYADMTGKEVIDYLTAVA-----QMKPDSGAYP-------QFANVSFVAK---DG--KLNDLKIKGEPVDPAKTYRMATLNFNATG------------------------------

General information: TITO was launched using: RESULT: Template: 1OI8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2286 64483 28.21 162.84 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 28.21 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.397

(partial model without unconserved sides chains): PDB file : Tito_1OI8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OI8-query.scw PDB file : Tito_Scwrl_1OI8.pdb: