Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSRSVCEKMTMTTENPNQTVVSHFFLEGLRYTAKHSSLFFLLFLLIYSITVAGNLLILLTVGSDSHLSLPMYHFLGHLSFLDACLSTVTVP----KVMAGLLTLDGKVISFEGCAVQLYCFHFLASTECFLYTVMAYDRYLAICQPLHYPVAMNRRMCAEMAGITWAIGATHAAIHTSLTFRLLYCGPCHIAYFFCDIPPVLKLACTDTTINELVMLASIGIVAAGCLILIVISYIFIVAAVLRIRTAQGRQRAFSPCTAQLTGVLLYYVPPVCIYLQPRSSEAGAGAPAVFYTIVTPMLNPFIYTLRNKEVKHALQRLLCSSFRESTAGSPPP 2Y03 Chain:A ((9-140)) ------------------------------QWEAGMSLLMALVVLLI----VAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTW-LWGSFLCELWTSLDVLCVTASIETLC----VIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRSRVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYCRSPDFRKAFKRLLA--------------

General information: TITO was launched using: RESULT: Template: 2Y03.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -89972 for 782 contacts (-115.1/contact) + 2D Compatibility (PS) -13092 + (NN) -3187 + (LL) 4508 1D Compatibility (HY) -12800 + (ID) 2150 Total energy: -116693.0 ( -149.22 by residue) QMean score : 0.107

(partial model without unconserved sides chains): PDB file : Tito_2Y03.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y03-query.scw PDB file : Tito_Scwrl_2Y03.pdb: