Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNGMNHSVVSEFVFMGLTNSREIQLLLFVFSLLFYFASMMGNLVIVFTVTMDAHLHSPMYFLLANLSIID--MAFCSITAPKMICDIFKKHKAISFRGCITQIFFSHALGGTEMVLLIAMAFDRYMAICKPLHYLTIMSPRMCLYFLATSSIIGLIHSLVQLVFVVDLPFCGPNIFDSFYCDLPRLLRLACTNTQELEFMVTVNSGLISVGSFVLLVISYIFILFTVWKHSSGGLAKALSTLSAHVTVVILFFGPLMFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTFRNKDMKVAMRRLCSRLAHFTKIL 1F88 Chain:A ((55-143)) -----------------------------------------NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTT--TLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAASATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPST

General information: TITO was launched using: RESULT: Template: 1F88.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -47553 for 509 contacts (-93.4/contact) + 2D Compatibility (PS) -9016 + (NN) -1235 + (LL) 3648 1D Compatibility (HY) -7600 + (ID) 1100 Total energy: -62856.0 ( -123.49 by residue) QMean score : 0.075

(partial model without unconserved sides chains): PDB file : Tito_1F88.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1F88-query.scw PDB file : Tito_Scwrl_1F88.pdb: