Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLMNYSSATEFYLLGFPGSEELHHILFAIFFFFYLVTLMGNTVIIMIVCVDKRLQSPMYFFLGHLSALEILVTTIIVPVMLWGLLLPGMQTIYLSAC----VVQLFLYLAVGTTEFALLGAMAVDRYVAVCNPLRYNIIMNRHTCNFVVLVSWVFGFLFQIWPVYVMFQLTYCKSNVVNNFFCDRGQLLKLSCNNTLFTEFILFLMAVFVLFGSLIPTIVSNAYIISTILKIPSSSGRRKSFSTCASHFTCVVIGYGSCLFLYVKPKQTQAADYNWVVSLMVSVVTPFLNPFIFTLRNDKVIEALRDGVKRCCQLFRN 4UG2 Chain:A ((18-164)) ----------------------------------VLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAI------AISTGFCAACHGCLFIACFVLVLTASSIFSLL-AIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSH

General information: TITO was launched using: RESULT: Template: 4UG2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -131283 for 934 contacts (-140.6/contact) + 2D Compatibility (PS) -14171 + (NN) -3141 + (LL) 3196 1D Compatibility (HY) -14400 + (ID) 1850 Total energy: -161649.0 ( -173.07 by residue) QMean score : 0.168

(partial model without unconserved sides chains): PDB file : Tito_4UG2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UG2-query.scw PDB file : Tito_Scwrl_4UG2.pdb: