Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDLTYIPEDLSSCPKFVNKILSSHQPLFSCPGDNVFGYDWSHDYPLFGNLVIMVSISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSIMRSVESCWYFGDGFCKFHTSFDMMLRLTSIFHLCSIAIDRFYAVCYPLHYTTKMTNSTIKQLLAFCWSVPALFSFGLVL----SEADVSGMQSYKILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSKQHARVISHVPENTKGAVKKHLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPILILDLLVWLRYFNSTCNPLIHGFFNPWFQKAFKYIVSGKIFSSHSETANLFPEAH 2YCY Chain:A ((28-298)) -----------------------------------------------GNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQD-PGCCDFVT---NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIR--D------RASKRKRVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLAF-----------------

General information: TITO was launched using: RESULT: Template: 2YCY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -218491 for 1944 contacts (-112.4/contact) + 2D Compatibility (PS) -26299 + (NN) 1898 + (LL) 3752 1D Compatibility (HY) -23600 + (ID) 4150 Total energy: -266890.0 ( -137.29 by residue) QMean score : 0.331

(partial model without unconserved sides chains): PDB file : Tito_2YCY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YCY-query.scw PDB file : Tito_Scwrl_2YCY.pdb: