Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----QINTPCSPSMLST--FTPCINFLRNSTA---------NGTSPTADCCKSLQTLTSGGRDCLCLIVTGSV-----PFQIPINRTLAISLPRACNMPGVPVQCKV 1S6D Chain:A ((1-103)) PYGRGRTESGCYQQMEEAEMLNHCGMYLMKNLGERSQVSPRMREEDHKQLCCMQLKNLD---EKCMCPAIMMMLNEPMWIRMRDQVMSMAHNLPIECNLM--SQPCQM

General information: TITO was launched using: RESULT: Template: 1S6D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -55752 for 556 contacts (-100.3/contact) + 2D Compatibility (PS) -7884 + (NN) 2468 + (LL) -352 1D Compatibility (HY) -4400 + (ID) 800 Total energy: -66720.0 ( -120.00 by residue) QMean score : 0.266

(partial model without unconserved sides chains): PDB file : Tito_1S6D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1S6D-query.scw PDB file : Tito_Scwrl_1S6D.pdb: