Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLTPKELDKLMLHYAGELARKRKEKGIKLNYVEAVALISAHIMEEARAGKKTAAELMQEGRTLLKPDDVMDGVASMIHEVGIEAMFPDGTKLVTVHTPIE-ANGKL----------------------VPGELFLKNEDITINEGKKAVSVKVKNVGDRPVQIGSHFHFFEVNRCLDFDREKTFGKRLDIASGTAVRFEPGEEKSVELIDIGGNRRIFGFNALVDRQADNESKKIALHRAKERGFHGAKSDDNYVKTIKE 3LA4 Chain:A ((1-247)) MKLSPREVEKLGLHNAGYLAQKRLARGVRLNYTEAVALIASQIMEYARDGEKTVAQLMCLGQHLLGRRQVLPAVPHLLNAVQVEATFPDGTKLVTVHDPISRENGELQEALFGSLLPVPSLDKFAEDNRIPGEILCEDECLTLNIGRKAVILKVTSKGDRPIQVGSHYHFIEVNPYLTFDRRKAYGMRLNIAAGTAVRFEPGDCKSVTLVSIEGNKVIRGGNAIADGPVNETNLEAAMHAVRSKGFGHEEEKDASEGFTKE

General information: TITO was launched using: RESULT: Template: 3LA4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -63700 for 1524 contacts (-41.8/contact) + 2D Compatibility (PS) -24258 + (NN) -12877 + (LL) 0 1D Compatibility (HY) -20800 + (ID) 5900 Total energy: -127535.0 ( -83.68 by residue) QMean score : 0.466

(partial model without unconserved sides chains): PDB file : Tito_3LA4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LA4-query.scw PDB file : Tito_Scwrl_3LA4.pdb: