Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPIVNMTDMLKKALAGKYAVGQFNINNLEWTQAILKAAEAEKAPVILGVSEGAAKYMGGFKTVVKMTEGLVEDLKITVPVAIHLDHGSSFDSCKAAIDAGFSSVMIDGSHHPIDENIAMTKQVVDYAHAKGVSVEAEIGTVGGDEDGVTGGINYADPQECLRVVKEANIDALAAALGSVHGPY----HGEPVLGFDEMKEISELTGAPLVLHGGS---------------------GIPEHQIKKAIELGHSKINVNTECQIVWTAAVREKLATDDKVYDPRKVIGPGVDAIIKTVTEKIQEFGSNGKA 2ISW Chain:A ((2-307)) -PLCTLRQMLGEARKHKYGVGAFNVNNMEQIQGIMKAVVQLKSPVILQCSRGALKY-SDMIYLKKLCEAALEK-HPDIPICIHLDHGDTLESVKMAIDLGFSSVMIDASHHPFDENVRITKEVVAYAHARSVSVEAELGTL----------VQLTEPQDAKKFVELTGVDALAVAIGTSHGAYKFKS----RLAIDRVKTISDLTGIPLVMHGSSSVPKDVKDMINKYGGKMPDAVGVPIESIVHAIGEGVCKINVDSDSRMAMTGAIRKVFVEHPEKFDPRDYLGPGRDAITEMLIPKIKAFGSAGHA

General information: TITO was launched using: RESULT: Template: 2ISW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -121493 for 2375 contacts (-51.2/contact) + 2D Compatibility (PS) -29830 + (NN) -12921 + (LL) -236 1D Compatibility (HY) -23600 + (ID) 6450 Total energy: -194530.0 ( -81.91 by residue) QMean score : 0.602

(partial model without unconserved sides chains): PDB file : Tito_2ISW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ISW-query.scw PDB file : Tito_Scwrl_2ISW.pdb: