Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTKAAVRNMRLEDIDHVYEIEASSFTSPWTKDSFYHELLENPYAHYLVIEKDGHLAGYCGIWI------------VMDDAQITNIAIKPEYRGQSLGETLFRSAVELCK-EKDARRLSLEVRVSNHPAQGLYKKFGMQPGGIRKNYYTDNGEDALIMWVTINE 4R3K Chain:A ((14-163)) ------LRNARMDDIDQIIKINRLTLPENYPYYFFVEHLKEYGLAFFVAI-VDNSVVGYIMPRIEWGFSNIKQLPSLVRKGHVVSIAVLEEYRRKGIATTLLEASMKSMKNDYNAEEIYLEVRVSNYPAIALYEKLNFKKVKVLKGYYAD-GEDAYLM------

General information: TITO was launched using: RESULT: Template: 4R3K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 605 -92083 -152.20 -672.14 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -152.20 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.461

(partial model without unconserved sides chains): PDB file : Tito_4R3K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4R3K-query.scw PDB file : Tito_Scwrl_4R3K.pdb: