Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALKAQNTISGKEGRLFLDGEEMAHIKTFEANVEKNKSEVNIMGRRMTGHKTTGANGTGTATFYKVTSKFVLLMMDYVKKGSDPYFT--LQAVLDDQSSGR----GTERVTL---YDVNFDS----AKIASLD-VDSEALEEEVPFTFEDFDVPEKLSDTF 3JRK Chain:A ((75-169)) ----------------------------------------------------------------RVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIAD--

General information: TITO was launched using: RESULT: Template: 3JRK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 211 -13123 -62.19 -162.01 target 2D structure prediction score : 0.36 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -62.19 2D Compatibility (Sec. Struct. Predict.) : 0.36 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.303

(partial model without unconserved sides chains): PDB file : Tito_3JRK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3JRK-query.scw PDB file : Tito_Scwrl_3JRK.pdb: