Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGGNQILKQIIAKHLLDIQAVFLRPNEPFTWASGILSPIYCDNRLTLSFPEVRNDVASGISKLVKEH--FPEAEMIAGTATAGIPHAALAADHLNLPMCYVRSKPKAHGKGNQIEGAVQEGQKTVVIEDLISTGGSVLEACAALQAAGCEVLGVVSIFTYGLPKAEEAFAK-AELPYYSLTDYDTLTEVALENGNIHSDDLKKLQTWKRNPESKDWFKK 4OHC Chain:A ((14-221)) ---RQSISDTTAKILLEVQAVHFNAEKPFIFTSGWASPVYIDCRKLISYPRVRRALMEMAETTITRDIGFEQIDAVAGGETAGIPFAAWIADRMMVPMQYVRKKPKGFGRNAQIEGHLEEGSRVLLVEDLTTDSRSKINFVNALRTAGATVNHCFVLFHYNIFKESVSVLKDIDVDLHALATWWDVLRVAKASGYFETKTLDEVEKFLHAP--------

General information: TITO was launched using: RESULT: Template: 4OHC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1033 -153522 -148.62 -748.89 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -148.62 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.619

(partial model without unconserved sides chains): PDB file : Tito_4OHC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OHC-query.scw PDB file : Tito_Scwrl_4OHC.pdb: