Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITYVFPGQGSQKQGMGSGLFDEFKELTDQADEILGYSIKRL---CLENPYSN----LNKTQFTQPALYVVNALSYLKKIRDEEVKPDFVAGHSLGEYNALFAAEAFDFETGLQLVRKRGELMSL---ISNGGMAAVMGLNEEQVAKALKEYHLHD--VDIANVNAPYQIVISGKK---DE-IEKAASLFETMTEVTMVLPLNVSGAFHSRYMNKAKEEFEEFLHAFYFSPPSIPVISNVYAKPYT-YEFMKQTLADQINHSVKWTDSISYLMKKGHMEFEEVGPGNVLTGLIHRIKKDAEAMPR 3IM9 Chain:A ((12-299)) -MAIIFPGQGAQKVGMAQDLFNN----NDQATEILTSAAKTLDFDILETMFTDEEGKLGETENTQPAL-LTHSSALLAALKN--LNPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANINCPGQIVVSGHKALIDELVEKGKSL-----GAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEVIKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVK----

General information: TITO was launched using: RESULT: Template: 3IM9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1555 -144269 -92.78 -532.36 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -92.78 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.520

(partial model without unconserved sides chains): PDB file : Tito_3IM9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IM9-query.scw PDB file : Tito_Scwrl_3IM9.pdb: