Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKPINIQDQFLNQIRKENTYVTVFLLNGFQLRGQVKGFDNFTVLLESEGKQQLIYKHAISTFAPQKNVQLELE 4NOY Chain:D ((8-71)) -----LQDYYLNQLRKEKILATVFLTNGFQLRGRVVSFDNWTVLLDVEGKQQLVFKHAISTFSPQKNVA----

General information: TITO was launched using: RESULT: Template: 4NOY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 228 -39634 -173.83 -619.27 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain D : 0.88 3D Compatibility (PKB) : -173.83 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.624

(partial model without unconserved sides chains): PDB file : Tito_4NOY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4NOY-query.scw PDB file : Tito_Scwrl_4NOY.pdb: