Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTTINQVYKHVGEEVTIGAWVANKRSSGK-IAFLQLRDGTGFIQGVVVKAEVEESIFQTAKSVTQETSLYIKGIVKE--DERSP------LGYELAVTDIEVIHEA-TDYP-ITPKEHGTEFLMDHRHLWLRSKRQHAIMKIRNEIIRATYEFFNNEGFVKVDPPILTGSAPEGTTELFATKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLQVQENYVSFIVQSVLKNCKIELNTLGRDTSKLEQIKAPFPRITYDEAIEFLKEKGFDD----IEWGDDFGAPHETAIAEHYDKPVFITRYPTSLKPFYMQPASDREDVVLCADLIAPEGYGEIIGGSERIHDMELLESRLKEHGLDSDAYKWYAELRKYGSVPHSGFGLGLERTVAWISGAPHVRETIPFPRLLNRLYP 3M4Q Chain:A ((25-451)) ------------GKLVTFKGWAYHIRKARKTLIFVELRDGSGYCQCVIFGKELCEP--EKVKLLTRECSLEITGRLNAYAGKNHPPEIADILNLEMQVTEWKVIGESPIDLENIINKDSSIPQKMQNRHIVIRSEHTQQVLQLRSEIQWYFRKYYHDNHFTEIQPPTIVKT------TLFKLQYFNEPAYLTQSSQLYLESVIASLGKSFCMLSSYRAE------HLAEYLHLEAELPFISFEDLLNHLEDLVCTVIDNVM---AVHGDKIRKMNPHLKLPTRPFKRMTYADAIKYCNDHGILNKDKPFEYGEDISEKPERQMTDEIGCPIFMIHFPSKMKAFYMSKVPGHPDLTESVDLLMP-GVGEIVGGSMRIWNYDELMGAYKANGLNPDPYYWYTQQRKYGSCPHGGYGLGVERLVMWLLGEDHIRKVCLYPRYLERCEP

General information: TITO was launched using: RESULT: Template: 3M4Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1819 -3709 -2.04 -9.27 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -2.04 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.495

(partial model without unconserved sides chains): PDB file : Tito_3M4Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3M4Q-query.scw PDB file : Tito_Scwrl_3M4Q.pdb: