Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSQLRKKTLEALSALSNEDILQKTERMYKYLFSLPEWQNAGTIAVTISRGLEIPTRPVIEQAWEEGKQVCIPKCHPDTKKMQFRTYQTDDQ---LETVYAGLLEPVIEKTKE--VNPSQIDLMIVPGVCFDVNGFRVGFGGGYYDRYLS------EYEGKTVSLLLECQLFAHVPRLPHDIPVHKLITEDRIISCFS 3HY3 Chain:A ((10-198)) -KRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQDEIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVREEALSTGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQICLQVPVN--DMKVDEVLYE--------

General information: TITO was launched using: RESULT: Template: 3HY3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 760 -50704 -66.72 -288.09 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -66.72 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.507

(partial model without unconserved sides chains): PDB file : Tito_3HY3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HY3-query.scw PDB file : Tito_Scwrl_3HY3.pdb: