Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNVAIVGDGGHGKVIRELINARSDTRLAAVLDDKFKTFEGGKEWYTGPPKAVTEL---RRLIPDVL-FLIAVGNNSVRKQLAERLGLGKDDFITLIHPSAIVSKSAVIGEGTVIMAGAIIQADARIGAHCIINTGAVAEHDNQISDYVHLSPRATLSGAVSVQEGAHVGTGASVIPQIIIGAWSIVGAGSAVIRSIPDRVTAAGAPARIISSIQTSNKG 4M98 Chain:A ((200-401)) -RKLAVIGAGGHGKVVAELAAALGTYGEIVFLDDRTQ------GSVNGFPVIGTTLLLENSLSPEQFDITVAVGNNRIRRQITENAAALGFKLPVLIHPDATVSPSAIIGQGSVVMAKAVVQAGSVLKDGVIVNTAATVDHDCLLDAFVHISPGAHLSGNTRIGEESRIGTGACSRQQTTVGSGVTAGAGAVIVCDIPDGMTVAGNPAK-----------

General information: TITO was launched using: RESULT: Template: 4M98.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1227 -34826 -28.38 -175.89 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -28.38 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.497

(partial model without unconserved sides chains): PDB file : Tito_4M98.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4M98-query.scw PDB file : Tito_Scwrl_4M98.pdb: