Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDFKQEVLDVLAEVCQDDIVKENPDIEIFEEGLLDSFGTVELLLAIENRFDILVPITEFDRDVWNTPNNIVNQLSELK 1HQB Chain:A ((7-81)) ---KNGVLDILADLTGSDDVKKNLDLNLFETGLLDSMGTVQLLLELQSQFGVDAPVSEFDRKEWDTPNKIIAKVEQAQ

General information: TITO was launched using: RESULT: Template: 1HQB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 270 -43386 -160.69 -578.48 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.86 3D Compatibility (PKB) : -160.69 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.618

(partial model without unconserved sides chains): PDB file : Tito_1HQB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1HQB-query.scw PDB file : Tito_Scwrl_1HQB.pdb: