Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTRTRSGSLAAGGLNWASLPLKLF--AGGNAKFWHPADIDFTRDRADWEKLSDDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFEEAKHTQVFRMWLDAVGISE-DLHRYLDDLPAYRQIFYAELPECLNALSADPSPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYGDQPPFDLSKDDFLQYSTDKGMRRFGTISNARGRPVAEIDVDYSPAQLEDTFADEDRRTLAAASA 4HR5 Chain:A ((28-250)) -------------IDWEHPMFKLYEKAKRNGK-WNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAG----TLDILPMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHND--HYKRIFYEALPEAMNRLYADDSPEAVIRAATVYNMIVEGTLAESGYYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWP------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4HR5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -114417 for 1635 contacts (-70.0/contact) + 2D Compatibility (PS) -22694 + (NN) -6577 + (LL) 5620 1D Compatibility (HY) -18800 + (ID) 4550 Total energy: -161418.0 ( -98.73 by residue) QMean score : 0.482

(partial model without unconserved sides chains): PDB file : Tito_4HR5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HR5-query.scw PDB file : Tito_Scwrl_4HR5.pdb: