Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIRIGTRGSLLATTQAATVRDALIAGG--HSAELVTISTEGDRSMAPIASLGVGVFTTALREAMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDD-VTETLEPVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGAIAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGARELMWGVRH 4MLQ Chain:A ((6-281)) -IIVGSRRSKLALTQTKWVIEQLKKQGLPFEFEIKEMV-------------------KEIEQAMLDKEIDMAVHSMKDMPAVLPEGLTIGCIPLREDHRDALISKNGERFEELPSGAVIGTSSLRRGAQLLSMRSDIEIKWIRGNIDTRLEKLKNEDYDAIILAAAGLSRMGWSKDTVTQYLEPEISVPAVGQGALAIECRENDHELLSLLQALNHDETARAVRAERVFLKEMEGGCQVPIAGYGRIL-----DGGNIELTSL---VASPDGKTIYKEHITGK-----------------------------

General information: TITO was launched using: RESULT: Template: 4MLQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -87039 for 2055 contacts (-42.4/contact) + 2D Compatibility (PS) -28049 + (NN) -18636 + (LL) 3948 1D Compatibility (HY) -18800 + (ID) 5250 Total energy: -153826.0 ( -74.85 by residue) QMean score : 0.463

(partial model without unconserved sides chains): PDB file : Tito_4MLQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MLQ-query.scw PDB file : Tito_Scwrl_4MLQ.pdb: