Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQV---KSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECE----RLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLARVDFFLTDDGP-VINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARGVGLH 4ME6 Chain:A ((21-372)) --------RKIRVGLIFGGKSAEHEVSLQSARNILDALDPQRFEPVLIGIDKQGQWHVND--PDSFLLHADDPARIALHRSGRGVAL-LPGAQQQ--QLRPIQ-------AQIDVVFPIVHGTLGEDGSLQGLLRMANLPFVGSGVLGSAVAMDKDMAKRVLRDARLAVAPFVCF--DRHT-AHADVDTLIAQLGLPLFVKPANQ---VGVSQVRTADAFAAALALALAYDHKVLVEAAVAGREIECAVL--GNAVPHASVCGEVV-----------------------EIVIPADIDAQTQQRIQQIAVQAYQALGCAGMARVDVFLCADGRIVINEVNTLPGFTRISVYPKLWQASGLDYRGLITRLIELALER-----

General information: TITO was launched using: RESULT: Template: 4ME6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -199811 for 2605 contacts (-76.7/contact) + 2D Compatibility (PS) -35376 + (NN) -22548 + (LL) 1904 1D Compatibility (HY) -37200 + (ID) 7400 Total energy: -300431.0 ( -115.33 by residue) QMean score : 0.638

(partial model without unconserved sides chains): PDB file : Tito_4ME6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ME6-query.scw PDB file : Tito_Scwrl_4ME6.pdb: