Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDPHHPHIQTHNAWVEFPIFDAKSRSLKKAVLGKAGGTIGRNNSNVVVIEALRDITMELNLGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGWA---------------KVTGRVAPVFDLGIGMDPEISGYENIIIRGLFLGQTRKQM--QAKVDEIAEFTELGEYLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDADFLRKAQSRLQNLVERSGILVFASHSNEFLARLCKTAIWIDHGVIRLAGGIEEVVRAYEGEDAARHVREVLAETQADRQNVQG 4YMW Chain:J ((14-240)) -------------------------------------------------LEVLKGVTLKVNKGEVVVIIGPSGSGKSTLLRCINLLEEPTKGEVFIDGVKINNGKVNINKVRQKVGMVFQ-HFNLFPHLTAIENITLAPVKVKKMNKKEAEELAVDLLAKVGLLDKKDQYPIK-LSGGQKQRLAIARALAMQPEVMLFDEPTSALDPEMVKEVLNVMKQLANEGMTMVVVTHEMGFAREVGDRVIFMDDGVIVEEGTPEEIFYRAKNERTREFLSKIL------------

General information: TITO was launched using: RESULT: Template: 4YMW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -133586 for 1663 contacts (-80.3/contact) + 2D Compatibility (PS) -22298 + (NN) -6193 + (LL) 3392 1D Compatibility (HY) -15600 + (ID) 3000 Total energy: -177285.0 ( -106.61 by residue) QMean score : 0.475

(partial model without unconserved sides chains): PDB file : Tito_4YMW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YMW-query.scw PDB file : Tito_Scwrl_4YMW.pdb: