Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEGISNFKTPSKLSEKKKSVLCSTPTINIPASPFMQKLGFGTGVNVYLMKRSPRGLSHSPWAVKKINPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTE-ANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEALETDV 2W5A Chain:A ((11-269)) ----------------------------------LYTIGTGSYGRCQKIRRKSDG---KILVWKELDYGSMT---EAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTK-ERQYLDEEFVLRVMTQLTLALKECHRRS--LHRDLKPANVFLDGK-QNVKLGDFGLARIL---TSFA---KTFVGTPYYMSPEQMN-RM-YNEKSDIWSLGCLLYELCALMPPFTAFSQ--------------KELAGKIREGKFRRIPYR-Y---SDELNEIITRMLNLKDYHRPSVEEILENPLILE

General information: TITO was launched using: RESULT: Template: 2W5A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -99065 for 1854 contacts (-53.4/contact) + 2D Compatibility (PS) -27416 + (NN) -21950 + (LL) 2660 1D Compatibility (HY) -16400 + (ID) 3000 Total energy: -165171.0 ( -89.09 by residue) QMean score : 0.480

(partial model without unconserved sides chains): PDB file : Tito_2W5A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2W5A-query.scw PDB file : Tito_Scwrl_2W5A.pdb: